The gelatin hollow capsule consists of two capsule shells, which are made from the combination of pharmaceutical gelatin and auxiliary materials. It is mainly used in the dressing of solid medicine. Such as homemade powder, health care products and pharmaceutical products, the user can solve the problem of difficult entrance and poor taste. In addition, the capsule can also be printed with words, trademarks and patterns, presenting a unique custom appearance.
The gelatin hollow capsule is a cylindrical shape, consisting of a hard and elastic hollow capsule consisting of a cap and body. The capsule should be clean, uniform color, smooth cut, no deformation, no odor. This product is divided into three kinds: transparency (two sections without sunscreen), semi-transparency (only one containing sunscreen) and opaque (two sections contain sunscreen).
Most capsules are made of gelatin. Gelatin is widely used in many foods, such as pudding, sweets, preserves, chewing candy, icing, food filling and dipping. In food, gelatin helps to solidify, thicken, stabilize and ventilate food. It is a popular, nutrient-rich and low-fat food ingredient. Gelatin itself is a water-soluble protein extracted from collagen, the main natural protein component of connective tissue. Gelatin is obtained from animal skin and bones through a controlled extraction process. There are many types of gelatin. The capsules are made from pharmaceutical grade gelatin, which meets stringent requirements for drug products. The procedure of the capsule is to form a layer of gelatin film on the stainless steel mould. Then the gelatine film becomes dry and hardened, forms the capsule, and then takes it from the mold. There are two kinds of moulds, one to make the capsule and the other to make the capsule cap.
(1) take the product 0.25 g, add water 50ml, heat to melt, cool, shake well, take solution 5ml, aggravate chromate test liquid - dilute hydrochloric acid (4:1), produce orange-yellow flocculation.
(2) extract 1ml of solution under the item (1), add water 50ml, shake well, and add tannic acid test number, which produces turbidity.
(3) take about 0.3g of this product, put in the test tube, add sodium lime a little, and the resulting gas can change the wet red litmus test paper to blue.
CCTV < > weekly quality report on April 15, 2012 broadcast "secret in the capsule", there are some illegal manufacturer exposure in hebei, jiangxi, zhejiang use heavy metal exceeds bid chromium industrial gelatin as edible gelatin to produce medicinal capsules. To modify the levels of heavy chromium in 13 batches of drugs used in nine pharmaceutical factories, such as pharmaceutical and tonghua jinma.
Several pharmaceutical companies have been exposed to excessive chromium levels in its medicinal hollow capsules, some of which are 90 times exceeded. The production enterprises use the raw lime to process the industrial gelatin made from leather waste to make capsules, and to drug companies. Police have intervened in the case, and four executives in zhejiang province have been brought under control.